Quotations
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Eric Nestler Quotes
«Our study provides a fundamentally new level of analysis by which we can better understand the actions of cocaine in brain-reward regions at the molecular level. It also points to new potential treatments for addiction.»
Author: Eric Nestler
«One of the cardinal features of addiction is how long-lived it is, ... A key question in the field has been: By what mechanisms do drugs of abuse cause changes in the brain that last this long?»
Author: Eric Nestler
«That would make addiction more inheritable than diseases we commonly think of as genetic, such as adult onset diabetes or common hypertension,»
Author: Eric Nestler
«That would make addiction more inheritable than diseases we commonly think of as genetic, such as adult onset diabetes or common hypertension.»
Author: Eric Nestler
«Maybe there's a faster or better way to treat depression if you approach the problem from two different directions.»
Author: Eric Nestler
«The social-defeat process induced production of BDNF in the reward circuit. Without BDNF in the circuit, an animal can't learn that a social stimulus is threatening and respond accordingly.»
Author: Eric Nestler
«Without BDNF in the circuit, an animal can't learn that a social stimulus is threatening and respond appropriately.»
Author: Eric Nestler
«Removal of BDNF before bullying, or treatment with antidepressants after bullying, both removed the behavioral abnormality observed.»
Author: Eric Nestler
«The challenge is to find a way to inhibit BDNF signaling within the reward pathway specifically. The many genes we show that are regulated by BDNF or antidepressants in this pathway may provide clues.»
Author: Eric Nestler
«Our study provides insight into how chronic stress triggers changes in the brain that are much more long-lived than the effects of existing antidepressants.»
Author: Eric Nestler